Osteochondral lesion with subchondral cyst in the proximal phalanx of the hallux secondary to gouty tophi treated with collagen membrane (AMIC): description of technique and case report

Authors

  • Arthur Hoelz Tellini Toledo Hospital das Clínicas da Faculdade de Medicina da USP, São Paulo, SP, Brazil
  • Danilo Ryuko Cândido Nishikawa Hospital Alemão Oswaldo Cruz, São Paulo, SP, Brazil https://orcid.org/0000-0003-0227-2440
  • Fabio Correa Paiva Fonseca Hospital das Clínicas da Faculdade de Medicina da USP, São Paulo, SP, Brazil https://orcid.org/0000-0002-8907-0472
  • Guilherme Honda Saito Hospital Sírio-Libanês, São Paulo, SP, Brazil
  • Alberto Abussamra Moreira Mendes Hospital Sírio-Libanês, São Paulo, SP, Brazil
  • Marcelo Pires Prado Einstein Hospital Israelita, São Paulo, SP, Brazil https://orcid.org/0000-0003-0325-8050

DOI:

https://doi.org/10.30795/jfootankle.2026.v20.2050

Keywords:

Collagen; Cartilage, articular; Membranes, artificial. Osteochondritis

Abstract

Gout is the most common cause of inflammatory arthritis in men, typically presenting with severe, acute pain in the first metatarsophalangeal joint. Osteochondral lesions secondary to gout are rare, and when they do occur, there is no consensus on the best treatment. The matrix-induced autologous chondrogenesis (AMIC) technique, when applied with a collagen membrane, has been shown to be an effective alternative for treating these lesions. The objective of this study was to describe the surgical treatment of an osteochondral lesion associated with a subchondral cyst, resulting from a gouty tophus in the proximal phalanx of the hallux, using the collagen membrane. Male patient, 23 years old, presenting osteochondral lesion in the proximal phalanx of the hallux, with involvement of the articular surface, secondary to a gouty tophus. Surgical treatment consisted of curettage of the subchondral cyst through a dorsal bone window, filling the defect with autologous bone graft, and repairing the lesion with collagen membrane. After a 2-year follow-up, the patient presented with complete pain resolution, with improvement on the visual analog scale (VAS) from 6 to 0 and an increase in the AOFAS score from 69 to 100. The patient fully resumed physical and daily activities without limitations. Considering a two-year follow-up period, the proposed treatment demonstrated satisfactory functional results, as evidenced by improvements in VAS and AOFAS scores.

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Published

2026-04-23

How to Cite

Toledo, A. H. T., Nishikawa, D. R. C., Fonseca, F. C. P., Saito, G. H., Mendes, A. A. M., & Pires Prado, M. (2026). Osteochondral lesion with subchondral cyst in the proximal phalanx of the hallux secondary to gouty tophi treated with collagen membrane (AMIC): description of technique and case report. Journal of the Foot & Ankle, 20(Suppl 1). https://doi.org/10.30795/jfootankle.2026.v20.2050