Anatomic pathological events in reparation of acute achilles tendons lesions in rats treated with platetelet-rich plasma

Authors

  • Francisco A. Cejas Rodriguez
  • Carlos Mauricio Figueredo Universidade Nacional de Córdoba. Faculdade de Ciências Químicas
  • Claudia E. Sotomayo Universidade Nacional de Córdoba. Faculdade de Ciências Químicas
  • Hugo A. Cejas Universidade Nacional de Córdoba

Keywords:

Achilles tendon/pathology, Tendons injuries, Platelet-rich plasma, Rats Wistar

Abstract

Objetive: The authors compare in anatomical and histopathological vision, the events in the healing of acutely injured Achilles tendons in two groups of rats. With and without the use of PRP respectively. Methods: We use 18 Wistar rats, where 5 were sacrificed to obtain PRP, 7 underwent surgical sections of his Achilles tendons and where treated with PRP and 6 underwent the same surgical sectoin, however not received the PRP. And we study the appearance of the surgical wound, and the Achille’s histopathology of representatives from both groups, in four differents postoperative periods of time. Results: A better infammatory response/repair in the groups treated with PRP was observed. Conclusions: The utilization of PRP means for faster and better healing of acute Achilles tendons. And this may serve as a stimulus for further studies in humans.

Author Biographies

Francisco A. Cejas Rodriguez

Ortopedia e Traumatologia, Torres, RS, Brasil.

Carlos Mauricio Figueredo, Universidade Nacional de Córdoba. Faculdade de Ciências Químicas

Departamento de Bioquímica Clinica, Argentina.

Claudia E. Sotomayo, Universidade Nacional de Córdoba. Faculdade de Ciências Químicas

Centro de Investigaciones em Bioquímica Clínica e Imunología.

Hugo A. Cejas, Universidade Nacional de Córdoba

Departamento de Patologia, Argentina.

Published

2015-12-12

How to Cite

Cejas Rodriguez, F. A., Figueredo, C. M., Sotomayo, C. E., & Cejas, H. A. (2015). Anatomic pathological events in reparation of acute achilles tendons lesions in rats treated with platetelet-rich plasma. Tobillo Y Pie, 7(2), 88–93. Retrieved from https://scijfootankle.emnuvens.com.br/tobilloypie/article/view/1471

Issue

Section

Original Articles